what is the role of albumin and plasma in hematemsis patients ?

 


Hematemesis is a medical condition characterized by the vomiting of blood, which can be caused by various factors such as peptic ulcer disease, esophageal varices, gastritis, or cancer. In patients with hematemesis, albumin and plasma play important roles in the management of the condition.


Albumin is a protein found in plasma and is synthesized by the liver. It helps to maintain the oncotic pressure in the blood vessels, which is essential for proper fluid balance in the body. In patients with hematemesis, the loss of blood can result in a decrease in the circulating blood volume and a decrease in the oncotic pressure. This can lead to edema and hypotension, which can be life-threatening. To address this issue, albumin may be administered to increase the oncotic pressure and restore fluid balance.


Plasma is the liquid component of blood that contains various proteins, including clotting factors, immunoglobulins, and albumin. In patients with hematemesis, the loss of blood can result in a decrease in the clotting factors, which can lead to coagulopathy and further bleeding. To address this issue, plasma may be administered to provide the necessary clotting factors and restore hemostasis.


In summary, albumin and plasma play important roles in the management of hematemesis by maintaining proper fluid balance and restoring hemostasis, respectively. These therapies should be used in conjunction with other treatments, such as endoscopy or surgery, depending on the underlying cause of the hematemesis.