Burkkit's Lymphoma

 

Rapid Notes for Management of Acute Ischemic Stroke

 

Normal Laboratory Values

 

Antibiotics Families and Spectrums

 

Causes of Oedema

 

Liddle's Syndrome

 

• it's inherited form of hypertension

• it's inherited in the form of Autosomal dominant pattern
• it's caused by mutation in the  SCNN1A, SCNN1B, SCNN1G genes
• these genes provide instruction for making subunit of protein complex called epithelial sodium channel ( ENaC ) may found on surface of kidney cells

• Normally ENaC open in response to signals that Na level in the blood is too low, which allow reabsorption of Na back to the bloodstream

• if mutations occure, the ENaC will increase on cell surface leading to increase Na reabsorption and K exceartion

Features :- 

• Begins usually early in life often in the childhood, some people aren't diagnosed until adulthood

• may be no additional signs or symptoms, but overtime if untreated, may develop heart disease or cerebrovascular accidents

• may suffer from signs and symptoms of hypokalemia as

                                      * muscle weakness

                                      * fatigue

                                      * constipation

                                      * heart palpitations

                                     * metabolic alkalosis
                           

Differential diagnosis of Hematuria